Is it possible to plug a 4 port USB hub into a kwilt mini shoebox so I can connect 4 hard drives?

The Shoebox mini can accommodate a USB hub connection, however if a hub is connected, the Mini can accommodate only one large hard drive and one USB key, anything more than that & you will need either a powered USB hub or a self-powered USB HD Drive.

This being said you may want to consider taking a closer look at our latest devices:

Kwilt2 includes: (3 x USB 2.0) &
Kwilt3 includes: (1 x USB 3.0 & 2 x USB 2.0) respectively.